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Engraftment Donor


Test Information

Test Name: Engraftment Donor

Performing Lab: Molecular Diagnostic

Synonyms: BM Engraft Donor
Engr Donor

Order Includes: BM Engraft Donor
Engr Donor

Turnaround Time: 10 days

Additional Interpretation: Chimerism following bone marrow engraftment is a leading cause of morbidity and mortality in the bone marrow transplant population. Peripheral blood cells arising from the recipient as well as the donor appear in the peripheral circulation. Early monitoring of this state is necessary to allow early intervention.

Methodology: Peripheral blood, bone marrow or buccal swab DNA from a donor in marrow transplant are amplified with the 16-locus Human STR panel (Promega PowerPlex 16 HS system) using PCR methodology and the PCR products are characterized by capillary electrophoresis on the VidieraTM NsD platform. From this, a donor allele profile is established.


CPT Code: 81265

 

 

Result Information

No Information Available

 

 

Specimen & Collection Information

Specimen Name: Whole Blood
Bone Marrow
Buccal Swab

Container Type: Pink Top (EDTA)
Lavender Top (EDTA)

Special Handling: Refrigerate

Specimen Volume: 4.00 mL of whole blood (pink top collection tube) and/or 0.5 mL of bone marrow (lavender top)

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Specimen Transportation & Storage Information

Storage and Transport:Blood, Bone Marrow, and Buccal Swab:
Deliver to the lab immediately. Remote Locations : Blood and Bone Marrow:
Do not spin. Store refrigerated at 2°C to 8°C.

Buccal Swab:
Store at room temperature.